Nucleate works with startups that leverage life sciences to transform industries
Company overview
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Glyphic Bio | Boston Launched 2021 Platform |
Protein sequencing platform for detection and identification of low-expression proteins, potentially including novel therapeutic targets. |
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AptaBridge | Boston Launched 2021 Therapeutics |
Aptamer design platform enabling linkage of monospecific components to create multi-specifics or alter pharmacokinetics, targeting immunoncology. |
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Kano Therapeutics | Boston Launched 2021 Platform |
DNA engineering platform leveraging M13 bacteriophage for scalable construction of gene-length ssDNA, targeting therapeutic production. |
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Concerto Biosciences | Boston Launched 2019 Therapeutics |
Patented, data-driven platform for engineering microbial communities with useful properties. |
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NextRNA | Boston Launched 2019 Platform |
NextRNA is transforming the non-coding RNA therapeutic space and is shifting the concept of undruggable into druggable. |
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Manifold Bio | Boston Launched 2019 Platform |
A novel experimental platform that generates pharmacological measurements on millions of therapeutic protein variants in parallel. |
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Acoustica Bio | Boston Launched 2019 Platform |
Improving clinical care of millions of patients by reformulating existing intravenously-delivered drugs in a subcutaneous form, using a patented acoustophoretic printing approach. |
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Beacon Biomimetics | Boston Launched 2020 Medical Devices |
Developd PhonoGraft, a novel device composed of a synthetic, biodegradable elastomer that can restore biomimetic stiffness in the tympanic membrane to improve hearing outcomes. |
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PionEar Technologies | Boston Launched 2020 Medical Devices |
Developing a new generation of fluid-guiding and biocontamination-resistant tympanostomy tubes that allow antibiotic drops to penetrate the middle ear more efficiently. |
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Limax Bio | Boston Launched 2021 Diagnostics |
Tissue adhesive combining high strength, high adhesion energy, and biocompatibility for wound healing across multiple tissue types. |
| Ilesa Bio | Boston Launched 2021 Therapeutics |
Biotherapeutic for shielding native gut microbiota from antibiotics, for prevention of dysbiosis-related inflammatory and metabolic disorders. | |
| Crisscross Nano | Boston Launched 2021 Diagnostics |
Diagnostic platform leveraging DNA nanostructures for rapid, low-cost detection of nucleic acids and proteins, initially targeting infectious disease. | |
| Carmel Medicine | Boston Launched 2021 Therapeutics |
Therapeutic neural growth factor (NGF) addressing the historically dose-limiting side effect of pain, initially targeting peripheral neuropathy. | |
| PhageLink | Boston Launched 2021 Medical Devices |
Genetically engineered, biocompatible hydrogel that is customizable for broad therapeutic applications in drug delivery and 3D printing in vivo. | |
| Kumuda | Boston Launched 2021 Platform |
In silico drug discovery platform analyzing protein interaction, structure, and drug target homology across the human genome to discover drug targets. | |
| MicroLife | Boston Launched 2021 Eco |
Creating a stable probiotic spray using a patented silk and trehalose technology to deliver an engineered microbe microenvironment. | |
| Syntrophia | Boston Launched 2021 Eco |
Creating assay kits to continuously monitor and supercharge biomanufacturing and fermentation processes using FISH-TAMB mRNA imaging technology. | |
| PicoGreens | Boston Launched 2021 Eco |
Developing a new type sustainable feedstock for biomanufacturing and cell culture processes, composed of fast-growing cyanobacteria. | |
| Farm Forward | Boston Launched 2021 Eco |
Generating plant tissue-like materials for a range of applications. | |
| Eat PET | Boston Launched 2020 Eco |
High performance enzymes and microbes to convert low-value plastics into high-value chemicals and products. | |
| Asan Therapeutics | Boston Launched 2020 Therapeutics |
Developing a drug delivery platform dedicated to making the delivery of biologics easier. | |
| CellBLAST | Boston Launched 2020 Platform |
Cutting-edge machine learning algorithms designed for multi-modal analysis of cell states and their underlying dynamic changes across conditions. | |
| Enplus One Bio | Boston Launched 2020 Therapeutics |
Novel enzymatic RNA oligonucleotide synthesis platform to produce custom RNA sequences comprised of natural and modified nucleobases; aim to address limitations of traditional chemical RNA synthesis methods. | |
| Karivez | Boston Launched 2020 Therapeutics |
Therapeutics company founded on technology that transports biologic drugs across epithelial barriers within the body, to enhance biodistribution and enable oral delivery of drugs that previously had to be injected or infused. | |
| Platelet Xploration | Boston Launched 2020 Diagnostics |
Aims to improve outcomes for patients with platelet-related disease; first project willl develop better tests to predict bleeding in immune thrombocytopenia. | |
| RCD | Boston Launched 2020 Platform |
Proprietary algorithm to discover gene targets for next generation chemotherapy using computational analysis. | |
| Salvos | Boston Launched 2020 Therapeutics |
T-cell therapy company developing cancer therapeutics by improving T-cell functions utilizing our novel immune cell engineering platform; enhancing T-cells to unlock the power of a patient's immune system to fight against cancer. | |
| SUPER | Boston Launched 2020 Diagnostics |
Microsampling immunoassay with superior sensitivity to full-scale solutions and a potentially lab independent workflow, based on programmable DNA synthesis technology. | |
| Akili | Boston Launched 2019 Diagnostics |
Cancer diagnostics using a novel machine learning approach. | |
| Auxono | Boston Launched 2019 Therapeutics |
Developing novel therapies against Hippo-YAP signaling pathway, with applications in liver cancer and uveal melanoma. |
AptaBridge
Kano Therapeutics
Limax Bio
Ilesa Bio
Crisscross Nano
Carmel Medicine
PhageLink
Kumuda
MicroLife
Syntrophia
PicoGreens
Farm Forward
Eat PET
Asan Therapeutics
CellBLAST
Enplus One Bio
Karivez
Platelet Xploration
RCD
Salvos
SUPER
Akili
Auxono
Past cohorts
| Glyphic Bio | Boston Boston Diagnostics |
Protein sequencing platform for detection and identification of low-expression proteins, potentially including novel therapeutic targets. | |
| Auxno | Boston Launched 2019 Therapeutics |
Developing novel therapies against Hippo-YAP signaling pathway, with applications in liver cancer and uveal melanoma. |
Auxno